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Diagnostic Systems

The DIAGNOSTIC SYSTEMS (DXS) research group is headed by six principal investigators and five junior research leaders with extensive industrial and academic experiences. The key competences of this team are geared towards adding high value to your strategic projects.

We consolidate in-depth theoretical and practical know-how ranging from areas such immuno-, molecular- and cellular diagnostics, to instrumental analytics and bio-sensor development, as well as compound and phyto extract activity screening.

Together with the Institute of Systems Engineering and the Institute of Information Systems our research group conceptualizes, designs and develops innovative automation and miniaturization solutions to bio-analytical challenges.


RESEARCH AREAS

The Diagnostic Systems Research Group focuses on four innovation domains:

Point-of-care (POC) diagnostics
• Point-of-care (POC) diagnostics & Lab-on-a-chip devices
• Miniaturized, portable or wearable sensor systems
• Efficient sampling & functionality integration
• Sophisticated capture molecules & detection systems
• Remote access & data management

Cellular systems
• Bioavailability (e.g. intestinal transport)
• Bioactivity (e.g. anti-inflammatory, anti-infectious)
• Biocompatibility (e.g. biopolymers)
• 3D models (e.g. cell-scaffold interactions)
• Microfluidics (e.g. cellular analytics)

Molecular diagnostics
• PCR or other amplification/detection methods
• Gene expression & Epigenetics
• Pathogen identification & typing
• Immunoassays (e.g. fluorescence, ECL-based)
• Multivariate, multiplex (e.g. microarrays, DNA-chips)

Phyto-actives
• Skin therapeutics (e.g. inflammation, infections)
• Reliable cellular assays
• Active ingredient transport
• Cosmetic (and pharma) market
• Pilot scale facilities at PhytoArk

 

SENIOR RESEARCHERS

Alain-François Grogg, Ph.D.
Chemistry, Phytochemistry, Bioactivity Screening

Marc E. Pfeifer, Ph.D.
In-vitro Diagnostics (IVD), Molecular Diagnostics, POC Diagnostics

Bruno Schnyder, Ph.D.
Biochemistry, Immunology, Cellular Systems

Jean-Manuel Segura, Ph.D.
POC Diagnostics, Assay Development, Detection Systems