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A computerized score for the automated differentiation of usual interstitial pneumonia from regional volumetric texture analysis

A confident CT diagnosis of classic usual interstitial pneumonia (UIP) can eliminate the need for an invasive surgical biopsy to confirm this diagnosis. This task is often challenging, particularly in less specialized practice centers without access to experts experienced in interstitial lung disease. We propose a novel computational approach for the automated classification of classic versus atypical UIP. A score is derived from regional volumetric texture analysis of CT images.