Hes-so Valais

Diagnostic Systems

The DIAGNOSTIC SYSTEMS (DXS) research group consolidates in-depth theoretical and practical know-how ranging from areas such immuno-, molecular- and cellular diagnostics, to instrumental analytics and bio-sensor development, including microfluidics and digital / data processing.

Together with the Institute of Systems Engineering and the Institute of Information Systems our research group conceptualizes, designs, and develops innovative automation and miniaturization solutions to bio-analytical challenges.

The Diagnostic Systems Research Group focuses on four innovation domains:


The Diagnostic Systems Research Group focuses on four innovation domains:

Point-of-care (POC) diagnostics
• Point-of-care (POC) diagnostics & Lab-on-a-chip devices
• Miniaturized, portable or wearable sensor systems
• Efficient sampling & functionality integration
• Sophisticated capture molecules & detection systems
• Remote access & data management

Cellular systems
• Bioavailability (e.g. intestinal transport)
• Bioactivity (e.g. anti-inflammatory, anti-infectious)
• Biocompatibility (e.g. biopolymers)
• 3D models (e.g. cell-scaffold interactions)
• Microphysiological systems (MPS)

Molecular diagnostics
• PCR or other amplification/detection methods
• Gene expression & HT-sequencing
• Pathogen identification & typing
• Immunoassays (e.g. fluorescence, ECL-based)
• Multivariate, multiplex (e.g. microarrays, DNA-chips)
• Cell-free DNA testing

Médical devices & sensors 
• Microfluidics
• Drug-delivery systems
• Data acquisition & processing
• Neuroscience
• Sensor functionalizations



Marc E. Pfeifer, Ph.D.
In-vitro Diagnostics (IVD), Molecular Diagnostics, POC Diagnostics, Regulator aspects

Bruno Schnyder, Ph.D.
Biochemistry, Immunology, Cellular Systems

Jean-Manuel Segura, Ph.D.
POC Diagnostics, Assay Development, Detection Systems

Alena Simalatsar, Ph.D.
Druy-delivery systems, Microfluidies, Signal acquisition and processing

Alexandre Kuhn, Ph.D.
HT-Sequencing and nanopore - based devices, Cell-freee DNA testing, Digital health 

Denis Prim
Head of Laboratory, Symposium Manager, Bioanalytics