Diagnostic Systems

Point-of-care (POC) diagnostics

• Solutions for demonstrators and prototypes
• System integration and miniaturisation
• Smart functionalised biosensors
• Sophisticated capture molecules and detection systems
• Efficient sample processing (including microfluidic cartridges)
• Innovative rapid testing
• Drug delivery systems
• Data acquisition and processing

Development and validation of methods

• Analytical methods based on peptides, proteins (e.g. ELISA, ECLIA) or nucleic acids (e.g. DNA chips)
• High-sensitivity approaches or multiplex (multi-analyte) approaches 
• Development of electrochemical, label-free (e.g. surface plasmon resonance, SPR) or magnetic-based assays
• Chemical and physical surface modifications for the development of biosensors
• Analytical monitoring and characterisation of molecules (e.g. LC-MS, capillary electrophoresis (CE), etc.) 

Cellular systems

• Bioavailability, biocompatibility testing
• Bioactivity assays
• 3D cellular models (host-pathogen-interactions)
• Microphysiological systems

Molecular diagnostics

• Identification of pathogens and antibiotic resistance genes
• Targeted and whole genome genetic testing
• Bioinformatics
• DNA and RNA sequencing  

Senior researchers

• Milica Jovic, PhD
  Electrochemistry, Biosensing, Microfabrication
  
• Alexandre Kuhn, PhD
  NGS sequencing and nanopore-based devices, Cell-free DNA testing, Digital health
• Marc E. Pfeifer, PhD
  In-vitro Diagnostics (IVD), Molecular Diagnostics, POC Diagnostics, IVD Regulatory aspects
• Denis Prim, Engineer
  Head of Laboratory, Bioanalytics, Symposium Manager
• Bruno Schnyder, PhD
  Biochemistry, Immunology, Cellular Systems
• Jean-Manuel Segura, PhD
  POC Diagnostics, Assay Development, Detection Systems
• Alena Simalatsar, PhD
  Drug-delivery systems, Microfluidics, Signal acquisition and processing
• Sarah Wegmüller, PhD
  Molecular Biology, qPCR / PCR method development, Nanopore sequencing